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Ozone Therapy For Back Pain

Ozone Therapy For Back Pain

Effectiveness and Safety

  • Ozone therapy is highly effective in relieving both acute and chronic back pain.
  • It is safe, convenient, and inexpensive.
  • Ozone has a short half-life of approximately 1 hour at room temperature.

Applications in Pain Relief

  • Used in relieving pain in degenerative disc disease.
  • Superior option compared to steroid use.
  • Can be administered as a first-line treatment.
  • Both intradiscal and intramuscular injection of oxygen-ozone are successful approaches.

Mechanism of Action

  • Reactivates the innate antioxidant system.
  • In disc herniation, ozone is injected into the disc space where it dissolves in interstitial water and forms H2O2 and hydroxyl radicals.
  • These radicals react with proteoglycans, leading to their breakdown, resulting in matrix degeneration with progressive shrinkage and disappearance of the herniated material.
  • The amount injected is 3–10 mL with an ozone concentration of about 30 μg/mL.
  • Shows a positive response in 70–80% of cases of patients with low spinal pain.

Additional Benefits

  • Acts as a pro-drug.
  • Inhibits inflammation, corrects ischemia and venous stasis.
  • Induces a reflex therapy effect by stimulating anti-nociceptor analgesic mechanisms.
  • Helps reduce pain, accelerate nerve tissue regeneration, slow degenerative disc disease, accelerate ligament healing, and facilitate fracture healing.
  • Very effective in alleviating osteoarthritis and several other joint-tendinitis affections.